Researchers have utilized AI-guided protein design to create a caffeine-operated dissociation system (CODS) that acts as a molecular 'off-switch' for engineered cells. This system allows for precise control over cellular functions, including dampening CAR T cell activity, offering a safer and more responsive approach to cell therapies. The development signifies a leap in designing biological systems with familiar molecules, potentially leading to more controllable and safer medicines.
Read the full article at Genetic Engineering News
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