A Phase 1 clinical trial at Charité—Universitätsmedizin Berlin has shown that CAR T-cell therapy significantly reduced disease activity in six patients with severe, treatment-refractory rheumatoid arthritis (RA), with three achieving sustained remission without medication. This breakthrough could offer a new therapeutic approach for RA by targeting B cells responsible for persistent inflammation and resetting the immune system. Further research is needed to confirm long-term efficacy and safety.
Read the full article at Genetic Engineering News
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