Researchers have developed a new method to enhance 3D spatial analysis from serial sections of multiplexed imaging data, addressing the limitations of costly volumetric data acquisition. This geometry-aware reconstruction module stabilizes sparse yet consistent 3D analysis by linking cell projections across adjacent sections and recovering single-cell centroids, enabling reliable structure-level analyses that are otherwise unreliable in 2D.
Read the full article at arXiv cs.CV (Vision)
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